Nutritional Stress as an Adverse Effect of Anti-Diabetic Medications

Drugs Inducing Insomnia as an Adverse Effect

Anti-diabetic medications: How to make a choice?

Diabetes is the third commonest chronic illness in children following asthma and epilepsy. More recently the overall prevalence of diabetes in children and adults continued to increase dramatically. In children, this has partially been contributed to by the pandemic of obesity. Understandably, this posed an economic burden on health authorities and countries dealing with significant morbidity o...

Anti - diabetic Effect of Sodium

Many attempts have been made to treat diabetes mellitus with oral medic ation, but none of them seems to have been successful. It has been known that a decoction of Eunymus alata sieb growing in Japan has a blood sugar lowering ac tion. The effective component was isolated, crystallized, and identified as oxaloacetic acid (OAA) by infrared spectral analysis . Stable salt of O AA (OAA sodium) wa...

Epigenetics and life-long consequences of an adverse nutritional and diabetic intrauterine environment

The phenomenon that adverse environmental exposures in early life are associated with increased susceptibilities for many adult, particularly metabolic diseases, is now referred to as 'developmental origins of health and disease (DOHAD)' or 'Barker' hypothesis. Fetal overnutrition and undernutrition have similar long-lasting effects on the setting of the neuroendocrine control systems, energy h...

Modulating gut microbiota as an anti-diabetic mechanism of berberine

Berberine, one of the main constituents of a Chinese traditional herb used to treat bacterial diarrhea, has an effect of lowering glucose, which has been recently confirmed by many studies. However, the mechanism of berberine's antidiabetic effect has not yet been well explained. Recent evidence suggests that the gut microbiota composition is associated with obesity and type 2 diabetes, which a...